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KMID : 0358419940370030566
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Korean Journal of Obstetrics and Gynecology
1994 Volume.37 No. 3 p.566 ~ p.570
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Successful Treatment of Cervical Pregnancy with Methotrexate : A Case Report
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이철규
신향미/전권희/안영준/황호원
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Abstract
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Cervical pregnancy is one of the most uncommon form of ectopic pregnancy in which the blastocyst implants within the cervical canal below the internal os of uterine cervix. Most cervical pregnancies are complicated by severe life threatening
hemorrhage
and usually result in abdominal hysterectomy as a life-saving procedure.
Because of her desire to maintain childbearing capacity, the patient was treated with alternative administration of MTX (1 mg/kg, intramuscularly) and leucovorin (0.1 mg/kg, intramuscularly). Follow up was done with serum beta hCG and pelvic
ultrasonography. Complete resolution of pregnancy was gained at 28 days after completion of 1st course methotrexate treatment and 21 day after uneventful endocervical curettage. Methotrexate and leucovorin treatment for cervical pregnancy may be
worth-while trial for preserving reproductive performance.
We present a case of a cervical pregnancy that was successfully managed with methotrexate and leucovorin.
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